FAQ about AMH

Frequently asked questions about Anti-Mullerian Hormone (AMH)

The following questions are for reference only. Please consult your doctor for the related treatment rather than relying information on the website.

What is ovarian reserve?

Ovarian reserve is the amount of quality eggs present in the ovaries.

A woman is born with approximately one to two million eggs. Her egg numbers will decline as they are lost through natural attrition and ovulation over her reproductive life, only around 400 eggs can be successfully ovulated, the rest will be lost through natural cell death (apoptosis). The rate at which eggs are lost through apoptosis varies between individual women and this is why each woman starts menopause at different age. There are about 25,000 follicles in the ovaries when women reach the age of 37, and not all of them can ovulate successfully.

What is Anti-Mullerian Hormone (AMH)?

AMH is a hormone secreted by follicles in the ovaries, which involves in maturation of follicles. As the ovarian reserve decreases, AMH level decreases as well, therefore AMH level can reflect female’s fertility.

Who is in a higher risk of having low ovarian reserve?

Woman who has a family history of premature menopause, had ovary surgery, suffered from severe endometriosis or had radiotherapy/chemotherapy in the past, has a higher risk of having low ovarian reserve.

Most patients have a regular period, and not every patient who suffered from low ovarian reserve has the risk factor mentioned above. Testing AMH level is a more reliable method for the diagnosis.

How do we evaluate ovarian reserve?

Ovarian reserve can be evaluated through hormonal check (FSH, AMH) and pelvic ultrasound. AMH blood test is more reliable compare to other tests, therefore it is used before fertility treatment.

How important is ovarian reserve test?

Low ovarian reserve has an impact on female’s fertility, even getting pregnant successfully, miscarriage rate is higher compared to others. Therefore, it is important to get checked earlier in order to arrange the most suitable fertility plan.

Do I need to take the test at specific days during menstrual cycle?

AMH level does not change during menstrual cycle, so the test can be taken at any time.

How should we interpret the test result?

The test result allows doctor to interpret female’s “ovary age”, sometimes “ovary age” can be older than female’s actual age. For example, a 35 year old woman has a “ovary age” of 40, which means she has a relatively low ovarian reserve. It is common that most of the women suffered from infertility has a low AMH, indicating low ovarian reserve and therefore difficult natural conception.

In fact, many women have an AMH level that is too low to be detected and the youngest patient is only 37 years old.

A high AMH level indicates that the patient may suffer from polycystic ovary syndrome (PCOS)

What to do if ovarian reserve is low?

Women are born with a fixed number of eggs and cannot produce more after birth, there is no way that can increase the number of eggs a woman has. We suggested having AMH tested if you are planning to have children. If ovarian reserve is quite low and cannot conceive within 6 months, get a fertility check-up first and decide an appropriate fertility method based on the couple’s physical condition. Early detection of any fertility issues can reduce the delay in conceiving and allow you to find a fertility schedule that suits you.

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